News
19.03.2019
CRYOPRESERVATION
Cryopreservation is one of the most significant recent advancements in assisted reproduction technology (ART). Although interest in human tissue cryopreservation has existed for more than 200 years, significant progress in reproductive applications has occurred only in the last two or three decades.
The development of slow-freezing techniques and vitrification technology, and expansion in various combinations of newer cryoprotectants, have considerably advanced the field of ART. Sperm, oocytes, and embryos can now be frozen at various stages of development, making treatment potentially safer and more effective.
The chief objectives of cryopreservation are to make gametes or embryos available for future use by individuals or couples undergoing infertility treatment, and to preserve future fertility options for individuals at risk of losing their reproductive potential. Cryopreservation also offers the opportunity to forestall pregnancy to a safer, more optimal time. This is important for patients who are at risk of ovarian hyperstimulation syndrome (OHSS), or who have poor endometrial receptivity.
Frozen embryo transfer (FET) is a procedure – a cycle – in which frozen embryos are thawed, then transferred to a uterus. The improved results of embryo cryopreservation have been an essential component of preimplantation genetic diagnosis and screening.
The improved results of embryo cryopreservation have been an essential component for preimplantation genetic diagnosis/screening, using trophectoderm biopsy and array comparative genomic hybridization (CGH microarray) or Next Gen Sequencing (NGS). Blastocysts can be frozen, and genetic testing performed before the blastocysts are transferred. Embryo cryopreservation offers a way to avoid repeated ovarian stimulation, optimizes achieving embryo-endometrial synchrony, and aids in single embryo transfer.
25.12.2018
EXPERMED - 2019
The founders of EFF Alex Michopulos and Maria Kyuchyuk will take part in the 3rd international EXPERMED Congress, which will be held in northern Cyprus from April 11 to April 14. Congress organizes the Turkish Society for the Preservation of Fertility. http://expermedcongress.com/
04.08.2018
Reproductive surgery in the 21st century
The result of infertility treatment can be assessed accurately by the monthly fecundity rate and the cumulative pregnancy rate (CPR). The monthly fecundity rate, decreasing over time, and the time needed to reach the ultimate CPR are key factors in decision making. Depending on the clinical assessment, infertility treatment will be either with in vitro fertilization (IVF)/assisted reproduction technologies (ART) or with a diagnostic laparoscopy associated with reproductive surgery, which thereafter my require require IVF/ART. The comparison of IVF/ART treatment versus reproductive surgery is therefore the wrong debate as the CPR’s of reproductive surgery and of IVF are additive. Decisions should be based on the ultimate CPR’s and on effort and time, not on personal preferences. The large majority of women with infertility should have a diagnostic laparoscopy during which reproductive surgery can be performed if needed. IVF/ART treatment without a diagnosis decreases the ultimate CPR and is not without potentially serious adverse effects. Having excellent reproductive surgery readily available to patients, similar to the availability of IVF would increase CPR in women with infertility and decrease the overall cost.
25.07.2018
July 25, 1978, Louise Brown appeared - the world's first child, conceived by the method of IVF.
Since then, July 25 is World Day of Embryology.
The first successful IVF was conducted by scientists from the United Kingdom - Robert Edwards and Patrick Steptou. In Russia, the first child, conceived with the help of IVF, was born on February 7, 1986.
In 1992, for the first time, ICSI (sperm injection into the cytoplasm of the oocyte) was successfully applied.
Over forty years of using assisted reproductive technologies with their help, over eight million babies were born. Now in the world there are about two million cycles of IVF and ECO-ICSI annually. Every year ART methods become more and more perfect. Efficacy of IVF in leading reproductive clinics is over 60%.
16.05.2018
According to the IFFC study, the age at first birth is ever increasing. In Europe, women aged 35 years or older accounted for 22.5% of all live births in 2013, compared with 17.7% in 20041. It is a well-documented reality that both women and men are less eager to procreate while young. Responsible factors include societal changes, the grip of work, career and technology, and the social media selling the dream of postponing motherhood “until the time is right.” Yet, the impact of age on reproductive ability places women at a disadvantage due to the finite number of oocytes and their continuous alterations in DNA integrity as female age advances.
03.05.2018
We propose to our clients a new method for selecting spermatozoa based on the magnetic activation of sperm apoptosis (Magnetic - Activated Cell Sorting) the MACS system.
All spermatozoa have a limited lifespan and this process ends with apoptosis (cell death). In sperm, where the process of apoptosis began, a high probability of fragmentation (rupture) of DNA. Such gaps, unfortunately, can not be detected with a microscope. The MACS system allows us to solve the most difficult problems of our clients.
09.04.2018
Magnetic resonance imaging (MRI) is the current reference standard for noninvasive imaging of the pelvis. In patients with infertility potentially earmarked for in vitro fertilization/intracytoplasmic sperm injection procedures, the distinction between adenomyosis and its mimics is extremely vital. This is highlights the vital role of MRI in the detection of subtle nuances of adenomyosis in infertility and the key imaging features of its associated conditions and mimics.